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<article xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" dtd-version="1.4" article-type="research-article" xml:lang="en"><front><journal-meta><journal-title-group><journal-title xml:lang="ru">Всероссийский научный журнал "Вопросы права"</journal-title></journal-title-group><issn publication-format="electronic">2949-0871</issn></journal-meta><article-meta><article-categories><subj-group><subject>Other</subject></subj-group></article-categories><title-group><article-title xml:lang="ru">Влияние раневых материалов из хитозана на пролиферацию стволовых клеток</article-title><trans-title-group xml:lang="en"><trans-title>Effect of wound materials from chitosan on stem cell proliferation</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Владимирова</surname><given-names>Анастасия Андреевна</given-names></name><name xml:lang="en"><surname>Vladimirova</surname><given-names>Anastasia Andreevna</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/><email>anna.lomakina87@mail.ru</email></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Кивистик</surname><given-names>Софья Владимировна</given-names></name><name xml:lang="en"><surname>Kivistik</surname><given-names>Sofia Vladimirovna</given-names></name></name-alternatives><xref ref-type="aff" rid="aff3"/><xref ref-type="aff" rid="aff4"/><email>sofia.kivistik@gmail.com</email></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Маккаева</surname><given-names>Алина Ислановна</given-names></name><name xml:lang="en"><surname>Makkaeva</surname><given-names>Alina Islanovna</given-names></name></name-alternatives><xref ref-type="aff" rid="aff5"/><xref ref-type="aff" rid="aff6"/><email>makkaevaalina987@gmail.com</email></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Ломакина</surname><given-names>Анна Алексеевна</given-names></name><name xml:lang="en"><surname>Lomakina</surname><given-names>Anna Alekseevna</given-names></name></name-alternatives><xref ref-type="aff" rid="aff7"/><xref ref-type="aff" rid="aff8"/><email>anna.lomakina87@mail.ru</email></contrib><aff-alternatives id="aff1"><aff><institution xml:lang="en">Assistant, Saratov State Medical University</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="ru">Ассистент, Саратовский государственный медицинский университет</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">Student, Saratov State Medical University</institution></aff></aff-alternatives><aff-alternatives id="aff4"><aff><institution xml:lang="ru">Студент, Саратовский государственный медицинский университет</institution></aff></aff-alternatives><aff-alternatives id="aff5"><aff><institution xml:lang="en">Student, Saratov State Medical University</institution></aff></aff-alternatives><aff-alternatives id="aff6"><aff><institution xml:lang="ru">Студент, Саратовский государственный медицинский университет</institution></aff></aff-alternatives><aff-alternatives id="aff7"><aff><institution xml:lang="en">Assistant, Saratov State Medical University Клиническая медицина 3.1.33</institution></aff></aff-alternatives><aff-alternatives id="aff8"><aff><institution xml:lang="ru">Ассистент, Саратовский государственный медицинский университет</institution></aff></aff-alternatives></contrib-group><pub-date pub-type="epub" iso-8601-date="2024-06-30"><day>30</day><month>06</month><year>2024</year></pub-date><issue>2</issue><fpage>25</fpage><lpage>28</lpage><history><date date-type="received" iso-8601-date="2024-04-29"><day>29</day><month>04</month><year>2024</year></date><date date-type="accepted" iso-8601-date="2024-06-27"><day>27</day><month>06</month><year>2024</year></date></history><abstract xml:lang="ru"><p>Хронические раны, вызванные различными заболеваниями (сахарный диабет, венозные заболевания и т. д.), ожоги, механические нарушения целостности ткани были и остаются социальной и медицинской проблемой. Регенеративная медицина – одно из относительно новых направлений в современной медицине, в котором применяются уникальные методы лечения для решения подобных проблем. Суть регенеративной медицины заключается в восстановлении повреждённой ткани с использованием донорских или собственных стволовых клеток человека. Хитозан – природный биополимер, материалы на основе которого помогают создать оптимальные условия для пролиферации молодых клеток и ускоренной регенерации. Цель исследования – выявление преимуществ и недостатков применения биополимера хитозана в современной медицине.</p></abstract><abstract xml:lang="en" abstract-type="summary"><p>Chronic wounds caused by various diseases (diabetes mellitus, venous diseases, etc.), burns, mechanical violations of tissue integrity have been and remain a social and medical problem. Regenerative medicine is one of the relatively new innovations in modern medicine, which uses unique treatment methods to solve same problems. The essence of regenerative medicine is the restoration of damaged tissue using donor or a person’s own stem cells. Chitosan is a natural biopolymer, materials based on which make it possible to create optimal conditions for the proliferation of young cells and accelerated regeneration. The purpose of the study is to identify the advantages and disadvantages of using chitosan biopolymer in modern medicine.</p></abstract><kwd-group xml:lang="ru"><kwd>раневые материалы</kwd><kwd>хитозан</kwd><kwd>стволовые клетки</kwd><kwd>регенеративная медицина</kwd></kwd-group><kwd-group xml:lang="en"><kwd>wound materials</kwd><kwd>chitosan</kwd><kwd>stem cells</kwd><kwd>regenerative medicine</kwd></kwd-group></article-meta></front><back><ref-list><ref id="ref1"><mixed-citation publication-type="other" xml:lang="ru">Печерский А.В., Печерский В.И., Шпиленя Е.С., Газиев А.Х., Семиглазов В.Ф. Рубцевание и регенерация // Вестник Северо-Западного государственного медицинского университета им. И.И. Мечникова. 2015. Т. 7, № 3. С. 73–82.</mixed-citation></ref><ref id="ref2"><mixed-citation publication-type="other" xml:lang="ru">Peipei Feng, Yang Luo1, Chunhai Ke, Haofeng Qiu, Wei Wang, Yabin Zhu1, Ruixia Hou1, Long Xu and Songze Wu. Chitosan-Based Functional Materials for Skin Wound Repair: Mechanisms and Applications // Frontiers in Bioengineering and Biotechnology. 2021. v. 9. no. 650598. p. 1-15.</mixed-citation></ref><ref id="ref3"><mixed-citation publication-type="other" xml:lang="ru">Лемперт А.Р., Логвинова Ю.С., Бычичко Д.Ю. и др. Структурно-функциональное исследование гемостатических покрытий на основе хитозана. // Бюллетень медицинской науки. 2021. №4(24). С. 81-87.</mixed-citation></ref><ref id="ref4"><mixed-citation publication-type="other" xml:lang="ru">Sankaralakshmi Gomathysankar, Ahmad Sukari Halim, Nik Soriani Yaacob. Proliferation of Keratinocytes Induced by AdiposeDerived Stem Cells on a Chitosan Scaffold and Its Role in Wound Healing, a Review // Archives of plastic surgery. 2022. v. 41. no. 5. p. 452-457.</mixed-citation></ref><ref id="ref5"><mixed-citation publication-type="other" xml:lang="ru">Прокапчук Н.Р. Меламед В.Д., Прищепенко Д.В. Инновационные раневые покрытия с нановолокнами хитозана // Труды БГТУ. 2017. Сер. 2. №1. С. 15-22.</mixed-citation></ref><ref id="ref6"><mixed-citation publication-type="other" xml:lang="ru">Борисов В.С., Боровкова Н.В., Сачков А.В. и др. Применение биодеградирующих раневых покрытий в лечении донорских и ожоговых ран у пациентов с термической травмой. // Актуальные проблемы медицины. 2023. Т. 46, № 1. С. 79–91.</mixed-citation></ref><ref id="ref7"><mixed-citation publication-type="other" xml:lang="ru">Ming Yang, Shuohai He, Ziyue Su, Zihang Yang, Xinxin Liang, Yingzhu Wu. Thermosensitive Injectable Chitosan/Collagen/-Glycerophosphate Composite Hydrogels for Enhancing Wound Healing by Encapsulating Mesenchymal Stem Cell Sphroid // ACS Omega. 2020. v. 5. p. 21015-21023.</mixed-citation></ref><ref id="ref8"><mixed-citation publication-type="other" xml:lang="ru">Ping Oi, Zhaohui Ning, Xiuju Zhang. Synergetic effects of 3D chitosan-based hybrid scaffolds and mesenchymal stem cells in orthopaedic tissue engineering // IET Nanobiotechnol. 2023. v. 17. p. 41-4.</mixed-citation></ref><ref id="ref9"><mixed-citation publication-type="other" xml:lang="ru">Mallesh Kurakula, Shashank Gorityala, Devang B. Patel, Pratap Basim, Bhaumik Patel, Saurabh Kumar Jha. Trends of Chitosan Based Delivery Systems in Neuroregeneration and Functional Recovery in Spinal Cord Injuries // Polysaccharides. 2021. v. 2. p. 519–537.</mixed-citation></ref><ref id="ref10"><mixed-citation publication-type="other" xml:lang="en">Pecherskij A.V., Pecherskij V.I., Shpilenja E.S., Gaziev A.H., Semiglazov V.F. Rubcevanie i regeneracija // Vestnik Severo-Zapadnogo gosudarstvennogo medicinskogo universiteta im. I.I. Mechnikova. 2015. T. 7, № 3. S. 73–82.</mixed-citation></ref><ref id="ref11"><mixed-citation publication-type="other" xml:lang="en">Peipei Feng, Yang Luo1, Chunhai Ke, Haofeng Qiu, Wei Wang, Yabin Zhu1, Ruixia Hou1, Long Xu and Songze Wu. Chitosan-Based Functional Materials for Skin Wound Repair: Mechanisms and Applications // Frontiers in Bioengineering and Biotechnology. 2021. v. 9. no. 650598. p. 1-15.</mixed-citation></ref><ref id="ref12"><mixed-citation publication-type="other" xml:lang="en">Lempert A.R., Logvinova Ju.S., Bychichko D.Ju. i dr. Strukturno-funkcional’noe issledovanie gemostaticheskih pokrytij na osnove hitozana. // Bjulleten’ medicinskoj nauki. 2021. №4(24). S. 81-87.</mixed-citation></ref><ref id="ref13"><mixed-citation publication-type="other" xml:lang="en">Sankaralakshmi Gomathysankar, Ahmad Sukari Halim, Nik Soriani Yaacob. Proliferation of Keratinocytes Induced by AdiposeDerived Stem Cells on a Chitosan Scaffold and Its Role in Wound Healing, a Review // Archives of plastic surgery. 2022. v. 41. no. 5. p. 452-457.</mixed-citation></ref><ref id="ref14"><mixed-citation publication-type="other" xml:lang="en">Prokapchuk N.R. Melamed V.D., Prishhepenko D.V. Innovacionnye ranevye pokrytija s nanovoloknami hitozana // Trudy BGTU. 2017. Ser. 2. №1. S. 15-22.</mixed-citation></ref><ref id="ref15"><mixed-citation publication-type="other" xml:lang="en">Borisov V.S., Borovkova N.V., Sachkov A.V. i dr. Primenenie biodegradirujushhih ranevyh pokrytij v lechenii donorskih i ozhogovyh ran u pacientov s termicheskoj travmoj. // Aktual’nye problemy mediciny. 2023. T. 46, № 1. S. 79–91.</mixed-citation></ref><ref id="ref16"><mixed-citation publication-type="other" xml:lang="en">Ming Yang, Shuohai He, Ziyue Su, Zihang Yang, Xinxin Liang, Yingzhu Wu. Thermosensitive Injectable Chitosan/Collagen/-Glycerophosphate Composite Hydrogels for Enhancing Wound Healing by Encapsulating Mesenchymal Stem Cell Sphroid // ACS Omega. 2020. v. 5. p. 21015-21023.</mixed-citation></ref><ref id="ref17"><mixed-citation publication-type="other" xml:lang="en">Ping Oi, Zhaohui Ning, Xiuju Zhang. Synergetic effects of 3D chitosan-based hybrid scaffolds and mesenchymal stem cells in orthopaedic tissue engineering // IET Nanobiotechnol. 2023. v. 17. p. 41-4.</mixed-citation></ref><ref id="ref18"><mixed-citation publication-type="other" xml:lang="en">Mallesh Kurakula, Shashank Gorityala, Devang B. Patel, Pratap Basim, Bhaumik Patel, Saurabh Kumar Jha. Trends of Chitosan Based Delivery Systems in Neuroregeneration and Functional Recovery in Spinal Cord Injuries // Polysaccharides. 2021. v. 2. p. 519–537.</mixed-citation></ref></ref-list></back></article>
